Human Immunoglobulin E (IgE) is a protein with a molecular weight of 190,000 daltons. It is composed of two heavy chains and a pair of light chains linked together by disulphide. A function of IgE is the immunity to parasites. In industrialized countries, IgE has also an important role in allergic reaction (type I hypersensitivity) such as asthma, dermatitis and food allergies. Elevated IgE levels in human serum are also observed in atopic diseases, rare myeloma and disorders related to T cell dysfunction (AIDS for example). IgE levels measurement in serum is mainly useful in the diagnosis, following and treatment of atopic diseases and parasitic infections.
Log in to access specific technical data sheets